Did you know that each of our 100 trillion cells has a biological clock? While cells efficiently replicate when we are young, this reproduction slows down as we become older. That is why our biological age and chronological age may differ. Read this article to learn how TA-65 may prevent this natural aging process.
TA-65: a Supplement for Anti-Aging
What Is TA-65?
TA-65 is a nutritional supplement extracted from Astragalus membranaceus’ dried root. This supplement can help maintain telomere length, which shortens as we age.
Astragalus membranaceus is valued for strengthening the immune system and metabolic and respiratory functions. The root of Astragalus membranaceus was used in traditional Chinese medicine to treat patients with chronic illnesses and healthy people who wanted to enhance their essential bodily functions. Recent studies have discovered that it can boost telomerase activity.
Telomeres are the caps at the end of DNA that protect our chromosomes. Think of it like the caps on your shoelaces. Each time the cell divides, your telomeres shorten. Eventually, the Telomeres shorten so much that your cells are unable to further divide. The edges of your chromosomes become “frayed” resulting in loss of function of the DNA. Therefore, telomere length is an buomarker of a person’s biological age. Short telomeres are associated with cellular aging, senescence, and malfunction.
Your cells have a mechanism to maintain telomere length. They contain telomerase, which is an enzyme that prevents telomeres from shortening. Some experiments have demonstrated that activating telomerase preserves telomere length, prevents aging, and reverses age-related tissue deterioration.
Astragalus Membranaceus in Making TA-65
Astragalus membranaceus (Huangqi) has a long history of medicinal usage as one of the most significant herbs in Traditional Chinese Medicine. Its long history of use is due to its capacity to enhance the immune system. Studies show that it can boost telomerase activity, which helps forestall human aging.
Astragalus membranaceus has some anti-aging and related effects such as:
- Oxidative stress reduction
- Immunomodulatory effects
- Anti-tumor effect
How Does TA-65 Work?
TA-65 may lengthen telomeres and slow down the aging process in cells. TA-65 enters the bloodstream and goes to individual cells throughout the body. It then penetrates through the cell membrane and activates telomerase. This telomerase enzyme reaches the ends of DNA strands and lengthens telomeres. Telomeres that have been extended can slow down the aging process and allow cells to replicate and divide. As a result, the cells are rejuvenated and are biologically younger.
By activating telomerase, TA-65 can:
- Prevent telomere shortening and cell aging
- Assist cells in living longer and functioning properly
- Make older cells younger
Has TA-65 Been Proven to Prevent Aging?
TA-65 was found in an empirical screen of natural product extracts from traditional Chinese medicines in 2000 and referenced as a small molecule telomerase activator. Since then, research and observational studies on TA-65 in people and animal models have supported improvements in aging biomarkers.
A study was conducted to find telomere length (TL) changes by taking TA-65 among 117 subjects aged 53 to 87 over one year. Ninety-seven subjects completed the study. Forty-five subjects received TA-65, while the other fifty-two subjects received a placebo during the 90-day study.
Compared to the placebo group, the group using TA-65 saw a rise in median TL at three months, followed by relative stability. At 9 and 12 months, TL in individuals receiving TA-65 was considerably more significant than in individuals taking placebo. In contrast, the average shortest quintile TL decreased gradually over time in the placebo group, as predicted. The study’s most important finding was that low-dose TA-65 (250 U) enhanced median and short TLs.
Many scientists have begun believing that TA-65 could have an essential role in fighting the natural aging process in humans. By activating an enzyme called telomerase, TA-65 allows the old cells to be healthier.
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