All About DHH-B (Magnolia Bark Extract): Why It is Better Than All Other Supplements for Stress Relief

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DHH-B in the pill form has appeared in drugstores and online stores as a viable supplement to heal a wealth of conditions.

Scientists have discovered that the compound may provide a wealth of pharmaceutical and medicinal benefits for improving health and wellness. Many studies have learned that the potent compound is anxiolytic, making it a promising treatment for mood disorders and depressive symptoms in modern medicine.

This is because it contains abundant anti-bacterial, anti-inflammatory, antidepressant, and anti-cancer properties, paving the way for more advancements in treatments of chronic conditions. Keep scrolling to learn about the basics of DHH-B and why it is a better stress relief supplement than the rest.


Magnolia Bark Extract DHH-B Can Be Your Next Go-to Stress Relief Supplement

What is DHH-B?

Dihydrohonokiol-B, or DHH-B, is a prenylated phenolic compound extracted mostly from the bark of magnolia trees. The compound is a more concentrated derivative of honokiol (magnolia bark), with findings estimating that its effectiveness is more substantial than often-referred magnolia bark supplement by up to 20 times.

As DHH-B can cross the blood-brain barrier, it delivers antioxidant and anti-inflammatory properties to protect delicate neurons from oxidative stress, preventing the development of neurodegenerative diseases like Alzheimer’s and Parkinson’s.


A Brief Look Into Magnolia Tree


Magnolia is a flowering plant recognized by many for their glossy green leaves and fragrant flowers in various colors, including ivory white, pale yellow, and light pink. The plant is indigenous to East and Southeast Asia, mainly China.

Scientists have discovered that the plant’s close ancestors existed 60-100 million years ago, even before the evolution of pollen messengers: bees. In other words, prehistoric plants shared the same home with dinosaurs.

More than a gardener’s favorite aromatic blooms, the magnolia tree has been a part of centuries-old Chinese and Japanese medicines due to its healing powers. Different tree parts, such as bark and flowers, have been used in medicinal applications.

The bark of the magnolia tree is widely valued because it contains two powerful polyphenols that provide many health benefits: magnolol and honokiol. These micronutrients derived from the plant are proven effective in defending against UV radiation and microbial infection.

Magnolia flowers and buds make delicious pickles and help alleviate headaches, allergies, and respiratory problems. Some even apply petals directly to heal inflamed gums.


DHH-B for Stress Relief: Understand The Magical Mechanism


Stress, anxiety, and depression are health-bummer conditions numerous people face due to hectic lifestyles, environmental stressors, and other factors. While we can’t avoid stress completely, seeking remedies is a must. Adopting a healthy mindset, exercising, counseling, meditating, and practicing mindfulness are some tips to overcome stress.

However, these might not work out for everyone. This has led people to rely on prescriptions when their stress levels are all over the place. However, some antidepressants are so sedative that they cause unpleasant side effects: drowsiness and motor impairments, making it difficult to remain conscious throughout the day. Addiction is another significant concern when overconsuming.

Lifting the spirit is probably why many seek DHH-B on the counter to tame their anxious thoughts. Plenty of scientific studies have backed the powerful compound’s effectiveness when it comes to busting stress. It is generally safe, natural, and, most importantly, produces little to no aftereffects.

What is the mechanism behind DHH-B? The all-natural compound helps lower anxiety and remove distressing thoughts in stressed people by boosting GABA activity.

GABA, an abbreviation for gamma-aminobutyric acid, is a bioactive agent produced by the brain. In stress management, GABA has the ability to calm the nervous system, preventing the transmission of certain signals. Such an activity is highly beneficial for supporting mood and managing stress. The well-known neurotransmitter is also useful for reducing high blood pressure, improving sleep, and healing muscle spasms. Research discovered that 40 healthy premenopausal women aged between 20 and 50 experienced reduced short-term and temporary anxiety without adverse side effects when consuming 250 mg of magnolia and Relora bark 3 times a day.

DHH-B also inhibits unhealthy levels of adrenaline and cortisol, two hormones released during flight or fight situations. While stress hormones motivate us to seek solutions, overflowing cortisol and adrenaline may wreak havoc on general health. A study investigating the effects of magnolia and Phellodendron barks found that people taking 500 mg of extract a day had significant cortisol drops, hence better overall mood. The consumption of DHH-B supplements helps reduce adrenal fatigue and promotes a greater sense of relaxation, calmness, vigilance, and alertness.

Another reason why DHH-B has been booming in popularity is due to its ability to stave off oxidative stress. Within a few short years, more and more people are worrying about free radicals, with stress being one of the leading causes. These bad guys, though tiny, can cause a chain of destruction to physical and mental health when roaming free within the body. Free radicals or oxidative stress are directly tied to a slew of life-threatening health conditions, including heart disease, strokes, and cancer, aside from wrinkles and gray hair. By reducing stress and anxiety, DHH-B also gives a helping hand in the battle against the generation of free radicals in the long run. Since DHH-B is rich in antioxidants, it helps to neutralize free radicals and prevent further damage caused by oxidative stress.


Other Benefits of DHH-B


  • DHH-B may aid in treating and preventing cancer because the compound can inhibit cellular division and neutralize the development of free radicals.
  • DHH-B may support stroke post-recovery, improving memory and enhancing cognitive functions and performance.
  • DHH-B may help prevent neural damage and promote the connections between nerve cells.
  • DHH-B may strengthen the immune system and play a role in the oxidation process.
  • DHH-B may help address and treat inflammation and chronic pain with a stronger immune system.
  • DHH-B may prevent cognitive decline related to aging, making it more manageable to combat neurodegenerative diseases without a cure, like Alzheimer’s.
  • DHH-B may improve sleep. Stress can cause poor sleep quality and insomnia. By cutting down stress, people may find it easier to fall asleep when taking DHH-B supplements.


Are There Any Side Effects?

Much like other supplements, it is always best to proceed with caution when starting DHH-B. It means going through the ingredient list or consulting a doctor to ensure safety before adding DHH-B to your supplemental regimen.

Even if the compound has been recruited in ancient medicines for millennia, more studies on humans are needed. Despite no serious side effects being reported, we still don’t know how it may interact with other medications and supplements.

Because DHH-B has a profound impact on the nervous system, beware of neurotoxicity when you consume over the recommended dosages. As DHH-B provokes sleep, do not take DHH-B before driving or mix it with sleeping pills and other sleep-inducing supplements.


Bottom Line

It is crucial to keep in mind that studies about the medicinal impact of DHH-B on humans are still limited despite promising outcomes on animals. Even if magnolia bark is natural and has been favored for centuries, always speak to a doctor for health and dosage assessment. Overall, taking DHH-B responsibly is advisable.




If you have questions about DHH-B or any health problems discussed here, contact us and learn more. 

At Peak Human, our team of healthcare professionals helps you reach your ‘peak’ health with a custom whole-person approach. Using the most cutting-edge, science-backed biohacking and aesthetic tools available today, we help you achieve the highest physical/cognitive performance state, improving your overall quality of life.

Don’t hesitate to contact us for questions or to book an appointment. Get personalized support and insight from expert physicians.

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