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All Posts By

Sanjeev Goel

“Fasting while Eating” – The Fasting Mimicking Diet (FMD)

By | Fasting, Food for thought

“Fasting while Eating” would seem to be an oxymoron and until recently I wasn’t aware that this is an ACTUAL thing. BUT IT IS…

The health benefits of Fasting are well established in the scientific community (and will be reviewed in future posts here). Even with such a preponderance of evidence, doctors have been leery of advising fasting because of the concern that adherence to this practices are quite difficult – many people do feel weak, tired, have headaches and could run the risk of malnutrition or electrolyte disturbances.

There are many different times of fasts:

1) Time restricted Feeding – abstaining from food from 8-16 hours per day
2) Intermittent Fasting – abstaining from food for 16 hours to 2 days
3) Periodic Fasting – abstaining from food for greater than 2 days to 21 days
4) Fasting Mimicking Diets – eating a diet that mimicks a fasting state for 5 days

Let’s skip right down to the 4th type – the Fasting Mimicking Diet.

Researchers led by Dr Valter Longo have devised a 5 day meal program what they claim provides all the health benefits of a 5 day fast but allows the participant to consume about 750 – 1000 kcal per day. The FMD diet being sold by Prolon has some good research behind it.

In a nutshell, the research study published in Science Translational Medicine (randomized and prospective crossover case control groups ) showed that participants that completed 5 days per month x 3 months (total 3 – 5 day fasts) of the Prolon fasting mimicking diet had lost fat, preserved lean body mass and their all their metabolic biomarkers improved (lipid, insulin growth factor 1, glycemic).

Furthermore, fat that was lost was primarily visceral (around organs) and abdominal and the good thing was that lean body mass was preserved.

This seems obvious – eating less food will result in weight loss – the good news from the studies was that the weight lost was primarily fat not protein (muscle).

But there really is one other big benefit that appeared in a study conducted with mice. Researchers noted that their was a decrease in the size of their livers during the study which rapidly grew back again once the fast ended. What appears to be happening is that the lowering of Insulin Growth Factor – 1 (IGF-1) allowing the cells to renew themselves – getting younger in the process. It appears that fasting kicks the body into a state of rejuvenation by activating our stem cells.

This is probably the mechanism behind why caloric restriction extends lifespan is all animals from the fruit fly to humans.

Faced with a scarcity of resources the body continues to remain youthful and not age BUT once we expose our bodies to an abundance of food and are past our optimum fertile stage of life (40+) the cells of the body send a signal to begin the decline that we notice as aging.

That’s a much longer discussion for another day…

Tomorrow, a bunch of us are doing the Prolon Fasting Mimicking Diet. Check how we are doing on Instagram and Facebook where we will be providing updates.

To learn more, I recommend reading “the complete guide to Fasting” by Dr. Jason Fung with Jimmy Moore.

Send us a message if this article helped you (bepeak@peakhuman.ca) and I’ll arrange to get a copy of the book shipped out to you.

Be Peak Now..

Blue Light Blocking Glasses – Biohack or Scam?

By | Biohacks

To be honest I was a bit sceptical when I first heard the idea about using blue light blocking glasses to improve sleep. I was reading the latest book by the BulletProof guru, Dave Asprey and his explanation for why this is a critical biohack that he uses in his life.

Then last year, during the Toronto Biohacker Summit that I hosted with the Biohacker Summit folks from Europe I met a bunch of other educated people who were sporting these yellow/orange tinged glasses in the evening!?!?? Sunglasses at night? I wondered if it was the “cool” factor.

So the premise of the health benefits of blue light blocking glasses is that blue light sends a signal to your brain through receptors in your retina. That blue light tells your brain that it is daylight so exposing your eyes to blue light in the evening will suppress melatonin secretion by your pineal gland.

Melatonin is the hormone that is released by the pineal gland in the brain in the evening to prepare your brain for sleep.

So do these glasses work?

In my experience and those who have tried them – all of them have noticed that they find it easier to fall asleep. Whether this translates into a deeper and longer sleep – that’s an interesting question that I am testing with the use of an Oura Ring that I just ordered.

I’ll keep you updated on my “experiments with truth” on this topic. If you want to experiment with me on how these glasses improve your sleep – send me a quick note to bepeak@peakhuman.ca and I’ll arrange to get a pair out to you.

What about Mk-677?

By | SARMs

You may have seen a bunch of websites on the internet promoting a category of supplements called “SARMs” that profess to help you build muscle and lose fat rapidly. In the gym, it is commonplace to hear about people using these performance enhancers in place of the traditional substances such as anabolic steroids and growth hormone. They do work when used properly but can still pose a risk if not monitored or dosed safely.

Before we discuss these new compounds, let’s talk about Growth Hormone – which has been used ubiquitously in bodybuilding and anti aging medicine circles up until 5 years ago. Chronic use of growth hormone eventually leads to tolerance and unwanted side effects due the prolonged stimulation of the cells of the body. Likely prolonged overuse – could cause your own growth hormone production to down regulate the receptors in the body to become irreversibly less sensitive. So there are problems….

So what about these new compounds?

One of these supplements is called MK-677. It is a peptide that are known as Growth Hormone Releasing Peptides (GHRP). GHRPs stimulate specific receptors of the cell of the pituitary gland to cause the cell to release Growth Hormone. Research has shown that this increases fat loss and muscle gain. Generally, the use of GHRPs are much safer than using Growth Hormone. But MK-677 still carries some risks – it is quite effective in increasing your own growth hormone release. But prolonged use can permanently down regulate the receptor on the cell making them less sensitive to your body’s endogenous Ghrelin (your body’s version of GHRP) production.

So if you are taking MK-677 – it is best to only take it for a few months at a time before cycling off it. The other issue to be aware of is that many of these compounds available on the internet may have contaminants or may not actually contain what’s advertised. Buyer Beware. Consult with a trained doctor in the use of peptides before you use these types of compounds.

If you are using Growth Hormone and want to come off it – you have options to do this and move onto a safer method while still getting benefits.

Peak X Labs Podcast Dr. Goel w Carmelia Ray

By | Peak X Labs Podcast | No Comments

Are you in Peak Sex condition? Listen to Peak X Labs Podcast where Dr. Sanjeev Goel talks with Celebrity Matchmaker Carmelia Ray about what options are available to be at the top of your game in the bedroom. What is the causes of Erectile Dysfunction? What about low libido in men and in woman? What type of testing can be done and are any treatments effective? All this and more (including enhancing the size of the penis) are discussed candidly.